HTTP/1.1 200 OK Cache-Control: no-cache, private Content-Type: text/html; charset=UTF-8 Date: Tue, 01 Dec 2020 03:05:43 GMT 莉莉影院在线观看 免费
Jump to main content
Jump to site search

Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

The term was first devised by psychologist Johan Denollet from Tilburg University who created a quiz to identify a type D personality.
The new image will replace that of Alexander Hamilton, the nation's first Treasury Secretary, whose portrait has graced the $10 bill since the late 1920s. The redesigned currency will debut in time for the 100th anniversary of the formal ratification of the constitutional amendment that gave women the right to vote.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Recipient: President-elect Donald Trump and Hilary Clinton (joint winners)
Romance was different then - with no computers, letter writing was the only way to stay in touch and remains more romantic than emails, he said.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 基本住房保障条例终止审议
Open Access Perspective

Soft matter science and the COVID-19 pandemic

节目35 歌曲《美丽中国》,沙宝亮 徐千雅

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

单词coach 联想记忆:

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

在360000个网红账号中,女性达到74%。而87.8%的网红年龄都在17-33岁之间,89%的网红接受过高等教育。
China's online retail volume is expected to outperform the rest of the world by reaching four trillion yuan (618 billion USdollars) this year, Commerce Minister Gao Hucheng said Sunday.
It is believed that the rise of South Korea's pop music industry is behind the boom, and many patients visit clinics with photos of celebrities, asking surgeons to emulate nose angle or eyes.
They say that it is especially risky to use the same password for entertainment sites as for email and social networking accounts.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

时间:2009-10-29 编辑:vicki
政府确实管了一些不该管、也不应属于自己管的事情,它束缚了市场主体的手脚,降低了行政效率,甚至影响了政府的公信力。
The CHIP, which retails for $150, can only bake four full-sized cookies at a time. If you were go the traditional way and bake a large batch in the oven, you'd have anywhere between eight and 12 cookies in under 30 minutes — and it's also cheaper.
你没有学到新的东西

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

单词fatigue 联想记忆:

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

小女孩名叫Neshama Spielman,来自耶路撒冷。她是4年前在“圣殿山筛选项目”中发现这个护符的。该项目旨在检查从神圣犹太教遗址移来,未经考古检测过的泥土。当年,Spielman只有8岁。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
From the themed collection: 北京共有产权住房建设进展顺利
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Rk&*IPgK1cOe4+
[ri'flekn]

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

根据Interbrand2016年全球最佳品牌报告显示,该榜单的前十名还包括微软、丰田汽车公司、IBM、三星电子有限公司、亚马逊、梅塞德斯-奔驰和通用电气公司。
Starting a business can wreak havoc on the owner’s personal life. While all the above tips are necessary for success, taking care of yourself mentally and physically is also imperative. Exercise, sleep and diet play a central role in ensuring you implement these policies successfully. All of them drive attitude, motivation and relationships.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 建立大湾区 绿色发展协调机制
Open Access Review Article

Diagnostic technologies for COVID-19: a review

格温o史蒂芬尼的广告在好几个应用上同时推出,其中就有总部位于硅谷的短信应用Tango。Tango主要通过用户收件箱里的广告赚钱,但它已采用了Swyft的平台,该公司广告和平台副总裁理查德o拉百特表示,这类广告非常契合人们使用Tango的方式。一年前,Tango决定不再卖贴纸了,因为向用户要钱总会带来很多摩擦。拉百特称:“在人们沟通过程中放上一道‘留下买路钱’的大门绝不是我们希望带给用户的体验。”所以,就由Swyft来提供这种广告吧。
继在电影《007:大破天幕杀机》中,和丹尼尔·克雷格(Daniel Craig)演对手戏,饰演神秘的塞芙琳(Severine)一角后,这名法国女星第二次挑战以英语为主要语言的角色。虽然电影《007:大破天幕杀机》在北美洲的公映时间是11月9号,但它已经在国际范围内开始向票房纪录发起进攻。

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: 佛山陶博会无大牌中小企业唱主角
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

从全国来看,上个月70个主要城市中62个城市的房价环比上涨,1个城市房价不变,还有7个城市出现下跌。
Experts offer advice for surviving -- and thriving -- in the next year:
2016全球大学国际化水平排名是由《泰晤士报》高等教育从28个国家的200所大学选出的。它采用了几项指标来衡量,比如国际员工的比例,国际学生的数量,每个学院至少有一个不同国家的作者合著的研究论文出版等。
3. 《间谍之桥》(Bridge of Spies)。几年前,史蒂文·斯皮尔伯格(Steven Spielberg)进入了殿堂级导演的行列,从安德鲁·萨里斯(Andrew Sarris)所谓的“美国电影”中借鉴了最崇高的形式——这部影片中他仍然保持水准。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
From the themed collection: 楼市错位去库存:大战才刚刚打响
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

奇才队如果想要留在强队之列,需要尽快给球队动手术。我们已经看到了他们一直以来期待的全员奇才是怎样的水准。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

The worst of 2015
然而,华尔街和硅谷对库克的态度转为欣赏,不仅仅是因为苹果本季度有望卖出7000万部iPhone,或者上季度销售额达到了420亿美元。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

[str?uk]

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

这造成了一种有待填补的身份认同真空。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Over time, this ethnic blend has led to an uncommon harmony among the current squad, whose young players -- notably Eden Hazard and Romelu Lukaku of Chelsea, and Adnan Januzaj 贾努扎伊of Manchester United -- are the envy of many of their competitors.
诺贝尔化学奖颁给了一位尝试制作世界上最小的分子机器的科学家。
人不得不告慰自己,原来如此。
比特币区块被讨论得最多的一项潜在用途,是去中心化的打车服务“Uber”。客户无需使用特定软件,就能订车并直接向司机付款,去掉中间商。(Uber创始人特拉维斯o卡兰尼克,抱歉)区块能用于各种用途,从储存安全文件(去中心化的的Dropbox)到“水印”技术,水印技术是指某块特定的比特币能包含比如你房子的房契。Digital Currency Group投资主管赖安o希尔基斯表示:“区块将催生数十年的创新。这可能催生零阻力股票发行、所有权转让以及智能合同。而上述事物共同构成了经济的支柱。如果你想创建分散管理的优步、Dropbox以及Facebook,你可以重塑互联网。”Digital Currency Group由前SecondMarket创始人巴里o希尔伯特创办。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

We Pay Attention … Selectively
3The United Kingdom
报告还发现,在当地政府的努力下,北京、深圳、广州、上海等一线城市的交通拥堵状况没有恶化。
“Thutmose III was one of the most important pharaohs in Egypt’s New Kingdom and is credited with establishing the Egyptian imperial province in Canaan,” said Gabriel Barkay, the co-founder and director of the Temple Mount Sifting Project.
In 2011 the owner of the tomb was identified as Liu Fei (169BC-127BC) the first king of Jiangdu an autonomous kingdom within the Han Dynasty according to China News.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

Yu Xiuhua, born with cerebral palsy, lived a quiet village life. She is now a literary sensation whose vivid, erotic poems are “stained with blood.”
9.《炫富帮》

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

The blocks of flats which were up to 12 storeys high in the city of Wuhan are making way for a huge new business district including a 707-metre tall skyscraper.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

“It’s horrible,” he said. “Whenever I see someone with a gun, I take it away and report it to police.”

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

[i'fektiv]
3.Video Editing: 19.2 percent increase
长话短说,1772年圣诞节后,Seppenwolde很快就破产了。这场灾难是当时荷兰报纸的头条新闻。它彻底毁了阿姆斯特丹一批商人和银行家。为了防止出现全面的信贷崩溃,阿姆斯特丹市只能作为最后贷款人暂时介入。这种情形是不是似曾相识?
This means war: Christopher Nolan's second film not set in the present (or future) is an epic tableau about the rescue of hundreds of thousands of troops from the French coast. Tom Hardy, Mark Rylance, Kenneth Branagh, Cillian Murphy and, er, Harry Styles, star. Think Saving Private Ryan, but saltier.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
From the themed collection: 十大新型建筑材料你都认识吗?
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

v. 挖隧道,挖地道
n. 饰带,花边,缎带
The bulk was due to underlying global warming caused largely by rising emissions of carbon dioxide, the main man-made greenhouse gas produced by burning fossil fuels, such as coal and oil.
n. 人口 ,(全体)居民,人数

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

TextPride changed its name to Swyft Media and launched a platform that pushes emojis and stickers from new brands into messaging apps. Brands pay for the privilege, as they would with a regular ad campaign.
Soon after he finished his duties, Sun heard loud voices coming from outside.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

支持:洛杉矶影评人协会将其评为最佳影片。
深化生态文明体制改革。
Anyone who doesn't feel they can tap into their inner-Picasso to create amazing drawings needn't worry. The study demonstrated that it wasn't the quality of the doodles and drawings that helped participants recall given words. Drawing a simple outline of a banana offered just as much benefit to the memory as a perfectly drawn piece of fruit. Additionally, the study found that participants only needed to spend a few seconds on their drawing to receive a significant boost to their ability to recall the word. The researchers plan to take their research a step further in the future by introducing more complex words and ideas and measuring the memory success of participants asked to recall those intricate thoughts.

然而,《秦时明月丽人心》并不能让更喜欢真实历史而非虚构故事的观众满意,该剧豆瓣评分仅为4.9分。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

从物业费到倒卖税,共管公寓和合作公寓的业主经常抱怨,管委会要将他们榨干了。不幸的是,运营建筑的成本在短时期内不会下降分毫。
扎克伯格还协助成立了一个名为FWD.us的游说团体,旨在推动美国的移民和教育改革。
James Bond is one of the few constants that movie lovers have in this crazy world of ours. We seem to know that, no matter what, a new Bond movie is always on the way.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

每天向大家推送短小精悍的英语学习资料.
But despite the anticipation, it seems the underwear brand's debut in the Chinese city is not going entirely to plan.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 乡村民宿:共享经济新体验
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
From the themed collection: 前8月全国棚户区改造开工465万套
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

[skr?ul]
Local-level work experience will advantageous for applicants, with personnel with more than two years of experience at this level given some advantage.
许多人在学习小组中受益良多。你得有条有理地进行,不能拖延时间。你要将学习的内容彻底消化,并能够向别人复述出来。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

Widely misunderstood as a biopic about the novelist David Foster Wallace, Mr. Ponsoldt’s film is a comedy of journalistic bad manners and a bitter, knowing satire of the machinery of literary fame. Jesse Eisenberg and Jason Segel use the conventions of the buddy movie to perfect a new subgenre: the frenemy film.
时间:2010-05-31 编辑:francie
鹈鹕一直在费力的吸引并留下自由球员,他们必须在这个夏天留下朱-霍勒迪,考辛斯的家乡在附近的阿拉巴马,而且他和安东尼-戴维斯是密友,同时,多个令人沮丧和伤病困扰的赛季让鹈鹕一直在失败的循环中摇摆。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

南韩的活动分子在星期二发誓,要在月底通过宣传气球跨越边境向北韩偷运荷里活讽刺片"刺杀金正恩",以作为对北韩不断威胁的反抗。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

Are you ready for a summer scare? Conjuring 2: The Enfield Poltergeist is set to hit the screens on June 10, 2016. We reckon that this is going to be a good horror movie.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Unlike several items on this list, artificial pancreas aren't still in some early development stage. The device very much exists and got FDA approval for sale this past September.
There are few chief executive decisions that drew more attention this year than Yahoo(YHOO, Fortune 500) CEO Marissa Mayer's work-from-home ban. The policy was initially seen as highly controversial and had a lot of people upset because of its perceived lack of flexibility.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

《每日经济新闻》引用一位专家的话称,银行业已经经历了一个低利润增长期,并且将持续很长一段时间。该专家表示,在过去的十几年里,银行业每年净利润增长达到35%至40%。但现在每年都不到1%,甚至有的银行都进入亏损状态。
To put this all in a bit more perspective, the current World Cup is averaging more goals than any of the top leagues around the world averaged in 2013/14. TheNetherlands' Eredivisie was the highest scoring of the top European leagues at 3.20 and the Bundesliga was just a shade behind at 3.16. No other top European league averaged more than 2.80 last season. In theAmericas, Major League Soccer is the current pace setter at 2.89 goals per game.
他说:“比如说,如果他们拖延从韩国进口的海关流程并采取对韩国商品的其他报复举措,韩国政府对此将无能为力。”
There is a natural human tendency to idealize and whitewash days of yore, to cast them in the rosy glow of the mind’s eye.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

在第三场也是最后一场总统候选人辩论中,奥巴马就外交政策发起攻势,一再指责罗姆尼在重大国际问题上的立场不坚定,但未能给他对手迅速崛起的竞选活动一个致命打击。
7、Bad body language habits

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 2014建材行业格局分析
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

The soaring prices of 2008, when oil reached more than $140 a barrel, will repeat, though not likely in 2014, Mr. Hummel said. The price 'is going to go higher.'
2) I Trust Your Judgment: Translation: “You have my permission. I believe in you. Now, go make it happen.” Feels pretty uplifting to hear that, doesn’t it? And I’ll bet you’d do almost anything to please someone who makes you feel that way. Your employees and peers are no different.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

n. 声明,陈述

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
From the themed collection: “便利店+”时代正在来临
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

So take a look. I sincerely hope you enjoy reading them as much as I liked selecting and editing them.
"They say: 'I wonder why she kept her head down in the meeting; I wonder why she's not eager to take over that project; I wonder why she's leaving early a couple days a week," Kay says. "You're planting questions in their head."
INDOORS: The two-story house, of brick and stucco with a ceramic tile roof, was designed by Dorr & Dorr, completed in 1916 and renovated over the last 15 years. The style is part Prairie, part Arts and Crafts, employing clean lines, open space, elegant woodwork and colored glass. Renovations were done by Joseph Metzler of Sala Architects in Minneapolis.
在Ross家附近的拐角处,一群男人坐在一家别墅的遮阳门廊,喝着啤酒,听着音乐。一个不愿意透露姓名的男人说,他从小就认识逮捕的这两个人。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

从周日起,各地的观众都在叹息该剧剧终,至少从Twitter名人的帖子来看是这样的。
Company: BlogHer

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

14. 《与外婆同行》(Grandma),导演:保罗·韦兹(Paul Weitz)。
新近成立的Eleven James正在男表领域引入合作消费的概念。该公司的会员项目能令你获得亲近一系列精挑细选的高端腕表的机会,这一曾经只和私人飞机、豪华汽车及度假屋联系在一起的会员模式正在Eleven James的手中发扬光大。除腕表外,会员还能注册专享忠诚度项目,其中包括礼宾服务、合伙人利益专享及诸如腕表主题活动等独一无二的体验。听起来有点像男士腕表和飞机租赁公司Net Jets体验的大碰撞?公司创始人兰迪?布兰多夫(Randy Brandoff)在奢侈品营销领域拥有深厚经验,曾经在Net Jets担任高级副总裁和首席营销官、在Marquis Jets担任过执行副总裁和首席营销官。他的专长,加上年复一年增长势头良好的腕表行业,以及一种在其他市场证明行之有效的商业模式——看起来Elven James正是在恰当的时间叩开了市场的大门。
4.无人驾驶的汽车

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

In global health, 2016 will be remembered as the year a little known virus made a major impact. It felt strangely familiar, but this time it wasn't Ebola making headlines around the world, it was Zika - a mosquito-borne virus being linked to a huge spike in the number of babies in Brazil born with brain defects.
他表示,2017年的目标是航班整体准点率维持在75%左右。
根据QS的这一排名,使得中国成为入选全球400强学校第二多的国家,仅次于有164所大学的学科入选全球400强的美国。英国排名第3,有78所大学进入榜单。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

据该报告显示,苹果的品牌价值同比去年增长了5%,至1780亿美元,而谷歌的品牌价值同比增长了11%,至1330亿美元。
Mavericks owner Mark Cuban has made riskier bets than this, though, and he didn't part with much of consequence (Justin Anderson and a fake first-round pick) for a shot at working Noel into a lob-finishing/rim-protecting life as the next Tyson Chandler.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

首先,正如咨询与培训机构RedPrairie公司的供应链专家汤姆?科赞斯基所言,一提到物流行业,多数人都觉得它“没有吸引力”,是一项乏味且薪水不高的仓储工作。
她表示:“美国宪法第一修正案中对于言论自由的保护仅针对公共实体的违法情况,而哈佛是所私立大学,所以第一修正案根本不适用。”
The city offers excitement beyond your expectations, with grand churches, a richly varied number of museums, a growing modern-art scene and streets that come alive with summer festivals.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

Against: Could the film be seen as a film of great performances, rather than a truly great piece of cinema
7. Amy Adams - $13.5 million

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

China saw its population grow last year, along with an improved male-female ratio and the level of education, according to a survey from the National Bureau of Statistics that was released on last Wednesday.
76人队在举步维艰地从一支历史悠久的全职摆烂大队向一支有竞争力地队伍转变;太阳队表现依旧不尽如人意。这两支显然是半垫底的球队了。但是他们至少没有对输球抓狂。
Now Chinese investment in western economies is back on track to break a further record this year: during the first six weeks this year Chinese groups have announced $70bn in potential deals, although the number is highly provisional and not all such acquisitions will be completed.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

54集电视连续剧《花千骨》绝对是刷爆朋友圈热门话题。2015年夏天播出以来,《花千骨》就名噪一时。这部由霍建华和赵丽颖主演的电视剧改编自Fresh果果的同名网络小说。这部改编电视剧颇具美感,中国水墨画风格的外景,加上盛世美颜的男女猪脚,成功吸引了80多万微博粉丝(《花千骨》电视剧官方微博)。该剧2015年6月首播,以女性的视角讲诉了一个孤儿成为女神的心路历程,以及她经历的旷世虐恋。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

It has to take over most of every waking minute. It's all you want to talk about. Prepare to watch people's eyes glaze over.
2008年,中国政府增加了一个归类为精神疾病的条目:"网瘾症"。据大量官方媒体报道,中国的年轻人花太多时间泡在网吧里,不顾家人和工作玩网络游戏到凌晨,有时甚至不吃,不喝,不睡眠,严重危害了自己的健康。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
From the themed collection: 印度或将成为最大LED照明系统市场
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

“Even though there is significant awareness [of the role of Fed policy], market dynamics can become unstable or unfavourable relatively easily,” he says. “Then you get into a self-reinforcing cycle of selling pressure.”
节目9 相声《这事儿不赖我》,曹云金 刘云天

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
From the themed collection: 海尔联姻 撬动智能家居千亿市场
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Play up being smarter than everyone, develop some obvious insecurities. Forget social skills if you happen to have any.
米其林(Michelin)、微软(Microsoft)、爱立信(Ericsson)等大企业的领导人已经把更多的决策权推向一线员工。随着这种方法的成功引起注意,其他企业将效仿。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
From the themed collection: 房屋限购家居企业该如何自处?
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

公众宗教研究机构与宗教新闻通讯社联合开展的这项调查显示,不同政治派别和不同宗教信仰的人们对于恶劣天气的观念存在分歧,今年已经发生了多起严重的高温和干旱灾害。
“That’s the difference between tweeting from your couch and governing the country. If you govern the country, you have to take sensible decisions, and that isn’t sensible,” Mr Rutte replied.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

Her piece, titled “Back to Mother Nature," depicts an elaborate water-cleaning machine. Zhang worked with a team of artists at Google to animate her drawing.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

'How do I explain the fact that I got a GQ Man of the Year award and no women's magazines and no women's organisations have supported me?
我照顾好自己了吗?有时候,我们太过于关心他人从而忘记了去照顾自己。这很容易就把自己遗忘。
在《醉乡民谣》(Inside Llewyn Davis)中,编剧兼导演乔尔?科恩(Joel Coen)和伊桑?科恩(Ethan Coen)兄弟俩挥之不去的忧伤情绪转化成了令人难忘的戏剧性场面。我觉得我的评论本应澄清,这部关于流行文化牺牲品的悲歌有一种特别的味道;其中一些部分相当阴郁。奥斯卡?伊萨克(Oscar Isaac)在片中出演一位自暴自弃的民谣乐手,宿命般地献身于他的艺术,他的卓越表演令这部影片极其震撼人心。
不存在什么人民,这是想象出来的实体。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

谎言1:不是我!说谎原因:有些事情不值得我们去邀功。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

n. 营养
由于孙轶潇没带手机,他开始尝试大声呼救以引起外面人的注意,但是时间一分一秒地流过,并没有人回应他。
7.《风流医生俏护士》主演未与剧组签合同

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
From the themed collection: 吉林省建材产业转型升级实施方案
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

5. 2012年搞笑诺贝尔奖之化学奖
The clip, taken on a mobile phone, starts with the crowd singing the Frankie Valli lyrics: You're just too good to be true, can't take my eyes off of you'.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

《老友记》大部分剧集拍摄之时,手机和Google都还未普及,剧中的服装和道具现在看来也有些过时,但是,剧中的主题却依旧深得现在年轻观众的心。
2. Smart water bottle

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

民主党能在中期选举中重新夺回美国众议院多数党地位吗?

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Sina's Weibo service, for example, has long offered features that Twitter lacks, notably a commenting function that allows multiple users to add their own thoughts to a user's posts. Tencent's QQ instant messaging service, which has more than 700 million users, offers additional features such as skins to change the look of the client and serves as a portal for the company to advertise other products and services. Sina declined to comment.
根据声明,通州新的行政中心将把基础设施升级和生态建设放在首位。北京市政府希望可以提高该地区的教育、医疗、文化事务与产业在内的公共服务发展。
专业一点

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

This compared to a decade ago when there were six Asian cities, 10 European cities and four US cities in the top 20 of the list that calculates living costs in 131 cities in 93 countries and is used by companies for costings when relocating staff.
在对入围的六本图书展开激烈辩论时,一名评委形容福特的书对该问题做出了“冷静而全面”的分析。英国《金融时报》主编兼此次评选委员会主席莱昂内尔巴伯(Lionel Barber)称《机器人的崛起:大规模失业的威胁与科技》“行文紧凑、研究深入,是公共政策辩论领域的又一佳作。”
如果你喜欢暖心且内容犀利的喜剧片,没有比《大病》更合适的了。这部影片讲述了一个喜剧演员爱上了一名抗议者的故事。他们的背景截然不同,这样的故事能让跨种族相爱的人产生共鸣。
报告显示,去年国内手机总出货量为5.6亿部,同比增长8%。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

随着《喜羊羊与灰太狼》大电影第二部《喜羊羊与灰太狼之虎虎生威》的上映,这部空前火爆的国产动画再度成为众人关注的焦点。你知道怎么用英文介绍《喜羊羊与灰太狼》么?I
If there are nine or 10 best picture nominees, it could grab a spot. Jordan Peele's screenplay looks certain to be recognized.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

随着他不断运用网络来搜集知识,达洛伊西奥意识到,他急需一个能让他快速确定文章阅读价值的方法。于是他构想了一个摘要工具,能运用语言学理论来编写低于400字的内容提要。
My Sunshine is a TV drama adapted from Gu Man`s novel of the same title. It stars Wallace Chuang and Tang Yan, premiering in January, 2015. The drama depicts a man and a woman`s reunion and long-lasting romance after seven years of separation. The novel itself has been popular on the Internet and was published in 2003. Wallace Chuang soon rose to become a romantic icon among female viewers because of the role he played in the adaptation, presenting an ideal image of lover to the audiences.
继8月中旬贬值后,人民币在9月和10月有所上涨,但在11月再度走低,昨日人民币汇率收跌至三个月最疲弱水平,为1美元兑6.4082元人民币。“中国周边很多国家自10月份起经历了一些资本外流,中国也未能幸免,”深圳招商证券(China Merchants Securities)经济学家谢亚轩表示。“美元走强势必在一定程度上引发转投美元资产的行为。”

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

About this collection

"He promised when he took office that he would have a Cabinet that was 50 percent women, and then he did it," Maddow said. "Would you make that same pledge?"
该报告还指出,那些在经济衰退期间不得已裁减支持型岗位的公司,也会“补充新人,以帮助各部门提高效率,提升生产力水平。”对于求职者而言,这一趋势无疑预示着一个美好的新年。

Spotlight

Advertisements